Georgia Institute of Technology College of Sciences

Taffy pullers are machines designed to stretch taffy. They can modeled by surface homeomorphisms, therefore they can be studied by geometry and topology. I will talk about how efficiency of taffy pullers can be defined mathematically and what some of the open questions are. I will also talk about Macaw, a computer program I am working on, which does related computations and which will hopefully help answer some of the open questions.

Antibiotics have greatly reduced morbidity and mortality from infectious diseases. Although antibiotic resistance is not a new problem, it breadth now constitutes asignificant threat to human health. One strategy to help combat resistance is to find novel ways of using obsolete antibiotics. For strains of E. coli and P. aeruginosa, pairs of antibiotics have been found where evolution of resistance to one increases, sometimes significantly, sensitivity to the other. These researchers have proposed cycling such pairs to treat infections. Similar strategies are being investigated to treat cancer. Using systems of ODEs, we model several possible treatment protocols using pairs and triples of such antibiotics, and investigate the speed of ascent of multiply resistant mutants. Rapid ascent would doom this strategy. This is joint work with Klas Udekwu (Stockholm University).

In Fall 2017 I will teach `Random Discrete Structures', which is an advanced course in discrete probability and probabilistic combinatorics. The goal of this informal lecture is to give a brief outline of the topics we intend to cover in this course. Buzz-words include Algorithmic Local Locasz Lemma, Concentration Inequalities, Differential Equation Method, Interpolation method and Advanced Second Moment Method.