Georgia Institute of Technology College of Sciences

Explosive technological advances lead to exponential growth of massive data-sets in health-related fields. Of particular important need is an innovative, robust and adaptive acquisition of intrinsic features and metric structure hidden in the massive data-sets. For example, the hidden low dimensional physiological dynamics often expresses itself as atime-varying periodicity and trend in the observed dataset. In this talk, I will discuss how to combine two modern adaptive signal processing techniques, alternating diffusion and concentration of frequency and time(ConceFT), to meet these needs. In addition to the theoreticaljustification, a direct application to the sleep-depth detection problem,ventilator weaning prediction problem and the anesthesia depth problemwill be demonstrated. If time permits, more applications likephotoplethysmography and electrocardiography signal analysis will be discussed.