Likelihood challenges for big trees and networks

Mathematical Biology Seminar
Wednesday, October 30, 2019 - 11:00am for 1 hour (actually 50 minutes)
Skiles 006
Claudia Solis-Lemus – University of Wisconsin-Madison
Hector BaƱos

Usual statistical inference techniques for the tree of life like maximum likelihood and bayesian inference through Markov chain Monte Carlo (MCMC) have been widely used, but their performance declines as the datasets increase (in number of genes or number of species).

I will present two new approaches suitable for big data: one, importance sampling technique for bayesian inference of phylogenetic trees, and two, a pseudolikelihood method for inference of phylogenetic networks.

The proposed methods will allow scientists to include more species into the tree of life, and thus complete a broader picture of evolution.