- Series
- Mathematical Biology Seminar
- Time
- Wednesday, March 16, 2016 - 11:05am for 1 hour (actually 50 minutes)
- Location
- Skiles 005
- Speaker
- June Zhang – CDC.
- Organizer
- Leonid Bunimovich
Accounting for Heterogenous Interactions in the Spread Infections, Failures, and Behaviors_ The
scaled SIS (susceptible-infected-susceptible) network process that we
introduced extends traditional birth-death process by accounting for
heterogeneous interactions between individuals. An edge in the network
represents contacts between two individuals, potentially leading to
contagion of a susceptible by an infective. The inclusion of the network
structure introduces combinatorial complexity, making such processes
difficult to analyze. The scaled SIS process has a closed-form
equilibrium distribution of the Gibbs form. The network
structure and the infection and healing rates determine susceptibility
to infection or failures. We study this at steady-state for three
scales: 1) characterizing susceptibility of individuals, 2)
characterizing susceptibility of communities, 3) characterizing
susceptibility of the entire population. We show that the
heterogeneity of the network structure results in some individuals
being more likely to be infected than others, but not necessarily the
individuals with the most number of interactions (i.e., degree). We also
show that "densely connected" subgraphs are more vulnerable to
infections and determine when network structures include these more
vulnerable communities.