Georgia Institute of Technology College of Sciences

After a few remarks to tie up some loose ends from last week's talk on locally ringed spaces, I will discuss exact sequences of sheaves and give some natural examples coming from real, complex, and algebraic geometry. In the context of these examples, we'll see that a surjective map of sheaves (meaning a morphism of sheaves which is surjective on the level of stalks) need not be surjective on global sections. This observation will be used to motivate the need for "sheaf cohomology" (which will be discussed in detail in subsequent talks).

The recent emergence of the influenza strain (the "swine flu") and delays in production of vaccine against it illustrate the importance of optimizing vaccine allocation.  Using an age-dependent model parametrized with data from the 1957 and 1918 influenza pandemics, which had dramatically different mortality patterns, we determined optimal vaccination strategies with regard to five outcome measures: deaths, infections, years of life lost, contingent valuation and economic costs.  In general, there is a balance between vaccinating children who transmit most and older individuals at greatest risk of mortality, however, we found that when at least a moderate amount of an effective vaccine is available supply, all outcome measures prioritized vaccinating schoolchildren.  This is vaccinating those most responsible for transmission to indirectly protect those most at risk of mortality and other disease complications.  When vaccine availability or effectiveness is reduced, the balance is shifted toward prioritizing those at greatest risk for some outcome measures. The amount of vaccine needed for vaccinating schoolchildren to be optimal depends on the general transmissibility of the influenza strain (R_0).  We also compared the previous and new recommendations of the CDC and its Advisory Committee on Immunization Practices are below optimum for all outcome measures. In addition, I will discuss some recent results using mortality and hospitalization data from the novel H1N1 "swine flu" and implications of the delay in vaccine availability.

Legendrian knots are knots that can be described only by their projections(without having to separately keep track of the over-under crossinginformation): The third coordinate is given as the slope of theprojections. Every knot can be put in Legendrian position in many ways. Inthis talk we present an ongoing project (with Etnyre and Ng) of thecomplete classification of Legendrian representations of twist knots.

Fourier's Law assert that the heat flow through a point in a solid is proportional to the temperature gradient at that point. Fourier himself thought that this law could not be derived from the mechanical properties of the elementary constituents (atoms and electrons, in modern language) of the solid. On the contrary, we now believe that such a derivation is possible and necessary. At the core of this change of opinion is the introduction of probability in the description. We now see the microscopic state of a system as a probability measure on phase space so that evolution becomes a stochastic process. Macroscopic properties are then obtained through averages. I will introduce some of the models used in this research and discuss their relevance for the physical problem and the mathematical results one can obtain.